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@#Introduction: Pesticides may influence the physicochemical properties of soil and the water quality parameters, which is vital in maintaining soil fertility and producing high quality crops. Objective: This study aims to determine the relationship between the concentration of pesticides, the physicochemical properties of the paddy soil samples and the water quality parameters of paddy water samples. Methods: A total of 72 soil and 72 water samples were collected in Tanjung Karang, Malaysia. The paddy soil and water were extracted using Quick, Easy, Cheap, Efficient, Rugged and Safe (QuEChERS) and solid phase extraction (SPE) techniques respectively. The concentrations of pesticides were analysed in ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS). The relationship of the concentration of target pesticides and the paddy soil and water physicochemical properties were studied using Spearman correlation. Results: In paddy soil, the concentration of propiconazole shows moderate positive correlation with manganese (Mn) (r = 0.587) (p≤ 0.01). Meanwhile buprofezin-total organic carbon (TOC) (r = -0.55) (p≤ 0.01), imidacloprid-cation exchange capacity (CEC) (r = -0.519) (p≤ 0.01), pymetrozine-sodium (Na) (r = -0.588) (p≤ 0.01), and trifloxystrobin-calcium (Ca) (r = 0.566) (p≤ 0.01) showed moderate negative correlation. Whereas in water, trifloxystrobin showed significant positive correlation with turbidity (r = 0.718) (p≤ 0.01) and tebuconazole showed negative correlation to dissolved oxygen (DO) (r = 0.634) (p≤ 0.01). Conclusion: The presence of pesticides in paddy field may influence the soil and water quality, thus regular monitoring of pesticides usage and nutrient management in soil is deemed important.
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@#Introduction: In Malaysia, herbal medicines are used for variety of reasons including health promotion and home remedies during pregnancy and postpartum with Manjakani (Quercus infectoria) as one of the most commonly consumed herbs. Herbal medicines consumption had been linked to heavy metals contamination and transfer from mother to infant and may affect infant’s growth and development. This study aims to (i) determine Manjakani consumption among postpartum mothers, (ii) quantify its heavy metals level, namely lead, cadmium, arsenic and chromium, and (iii) determine health risk associated with its consumption. Methods: A cross-sectional study involving 106 postpartum mothers was carried out in Kuala Lumpur. Six samples of Manjakani were sampled and extracted using microwave digester and analysed using Inductively coupled plasma mass spectrometry (ICP-MS). Non-carcinogenic health risks for herbal medicine consumption were calculated using Hazard Quotient (HQ). Results: Manjakani was consumed by 16% of mothers (n=17). Highest level of the metals was shown by chromium with mean concentration of 4210 ± 1910 ug/kg, followed by lead (170.8 ± 193.2), arsenic (39.3 ± 27.1) and cadmium (7.7 ± 0.76). There were no significant non-carcinogenic health risks with lead, arsenic, chromium and cadmium contamination (HQ < 1). Conclusion: Manjakani is consumed by mothers during confinement period. Heavy metals were quantified in Manjakani although no significant association was observed with socio-demographic characteristics and birth outcomes.
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@#Introduction: Consumption of Chinese Herbal Medicine (CHMs) have escalated globally. They are preferred treatment for minor diseases or disorders. In Malaysia, CHMs are common home remedies during pregnancy and postpartum. Angelica sinensis (Danggui) is a staple CHMs during postpartum for purpose of nourishing blood and resolving stasis. Concerns are raised over possible heavy metals toxicity. Objective: This study aims to (i) determine Danggui consumption among postpartum mothers, (ii) quantify its heavy metals level, namely Lead (Pb), Cadmium (Cd), Arsenic (As) and Chromium (Cr) and (iii) determine health risks of Danggui consumption among mothers. Methods: A cross-sectional study involving 112 postpartum mothers was carried out in Kuala Lumpur. Danggui samples were collected from nine districts in Kuala Lumpur (Segambut, Seputeh, Cheras, Kepong, Bandar Tun Razak, Titiwangsa, Setiawangsa, Batu and Lembah Pantai). Heavy metals were extracted using microwave digester and analysed using Inductively coupled plasma mass spectrometry (ICPMS). Hazard Quotient (HQ) was used to determine non-carcinogenic health risks for herbal medicine consumption. Results: Danggui was consumed by 19.6% of mothers (n=22). Among them, incidence of jaundice was 63.6% and need for phototherapy was 40.9%. Heavy metals contaminations were found in the decreasing order of Cr > As > Pb > Cd with median (interquartile) of 3996.3 (2805.6) μg/ kg, 128.3 (56.7), 98.6 (99.1) and 37.0 (35.0) respectively. No non-carcinogenic health risks were found for all four metals. Conclusion: Alarming concentrations of heavy metals were quantified in Danggui warranting for further investigation to safeguard health of postpartum mothers.
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Abstract@#Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants with toxic effects and adverse health impacts on general population. Several methods of extraction had been applied to extract PAHs from human blood samples such as solid phase extraction (SPE). The SPE represents one of the most common techniques for extraction and clean-up procedures as it needs low quantity of solvents with less manual efforts. Similarly, various analytical instruments like gas chromatography coupled to mass spectrometry (GC-MS) was used to measure the PAHs levels. Gas chromatography is a simple, fast, and very efficient method for solvents and small organic molecules. This review provides an overview of the measured concentrations of PAHs in human blood samples through the application of SPE and GCMS during the last ten years. While these studies used various solvents, their application of SPE method and GC-MS revealed rewarding results about the determination of PAHs levels in the human samples.
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@#Introduction: Tanjung Karang is a paddy growing town in Selangor, Malaysia. The paddy farmers in Tanjung Karang were using pesticides to control pests from invading the crops during agricultural activities with limited knowledge of its deleterious effects on their health. Objective: This study aims to (i) determine the respiratory health symptoms of paddy farmers due to occupational exposure of commonly used pesticides through inhalation and (ii) assess correlations between climatological conditions and the concentrations of pesticides in personal air samples among paddy farmers in Tanjung Karang, Malaysia. Methods: A cross-sectional study was carried out to assess the occupational exposures to pesticides among 83 paddy farmers in Kampung Sawah Sempadan. The data were collected with face-to-face interviews with the farmers based on a set of questionnaire. Results: The self-reported respiratory health symptoms of paddy farmers were as follows: breathing difficulty (16.9%), chest pain (15.7%), cough (41.0%), phlegm (39.8%), and wheezing (18.1%). Simple logistic regressions analysis indicated that exposure to azoxystrobin, buprofezin, chlorantraniliprole, fipronil, isoprothiolane, pretilachlor, propiconazole, tricyclazole and trifloxystrobin were contributing factors that affect self-reported respiratory health symptoms in this study. Spearman’s correlation coefficient test stated that the concentrations of chlorantraniliprole, fipronil and pymetrozine were affected by wind speed and temperature. Conclusion: The information obtained in this study is useful to understand the exposure of pesticides among paddy farmers and useful for risk management in the agricultural community.